ORGANUM
The depressive episodes in bipolar disorders are similar to those seen in unipolar depressive disorders. Many experts in the field feel that they are quantitative differences in the episodes experienced by bipolar patients; researchers have attempted to find this difference albeit it elusive.
Although the data is inconsistent and controversial, some clinicians report that the depressed patients who we prospectively diagnose as Bipolar tend to have hypersomnia, psychomotor retardation, psychotic symptoms, a history of postpartum episodes, a family history of bipolar type I disorder, and a history of anti-depressant induced hypomania.
Bipolar | Unipolar | |
|---|---|---|
History of mania/hypomania | Yes | No |
Temperament and personality | Cyclothymic (emotional reactivity and affective dysregulation) and extroverted | Dysthymic and introverted |
Sex ratio | Equal | Women > Men |
Age of onset | Teens, 20s and 30s | 30s, 40,s and 50s |
Postpartum episodes | More common | Less common |
Onset of episodes | Often abrupt | More insidious |
Number of episodes | Numerous | Fewer |
Duration of episodes | 3-6 months | 3-12 months |
Psychomotor activity | Retardation > agitation | Agitation > Retardation |
Sleep | Hypersomnia > Insomnia | Insomnia > Hypersomnia |
Family history | ||
Bipolar disorder | + | +/- |
Unipolar disorder | + | + |
Alcoholism | + | + |
Pharmacological response | ||
Antidepressants | Induce hypomania-mania | +/- |
Lithium Carbonate | Prophylaxis | +/- |