ORGANUM

Stroke syndromes

There are classical presentation of strokes based on the arterial territory that is affected. These are referred to as a 'Stroke Syndromes' and consist of dominant and non-dominant MCA infarction, medial and lateral medullary syndromes, anterior and posterior cerebral artery syndromes, and basilar artery syndromes.


Anterior cerebral artery syndrome

  • Contralateral hemiparesis of lower limbs

  • Contralateral sensory loss of lower limbs

  • Anosmia; olfactory bulb is infarcted

Anterior cerebral artery syndromes tend to be rare as the anterior communicating artery allows collateral blood flow


Alien hand syndrome (anterior corpus callosum or anterior cingulate)

  • Independent motor activity of the left limb - usually relatively complex activity, some apparently goal-oriented, and all of it entirely involuntary)

  • This happens from infarction of A4 and A5, which are the smallest branches of the anterior cerebral artery which supply the corpus callosum


Gerstmann syndrome : Whole of the dominant MCA

  • Agraphia

  • Acalculia

  • Finger agnosia

  • Right-left disorientation

  • Contralateral weakness

  • Contralateral sensory loss

  • Contralateral hemineglect

  • Contralateral homonymous hemianopia

  • Global aphasia (receptive and expressive)


Inferior division of dominant MCA

  • Contralateral homonymous hemianopia or upper quadrant anopsia

  • Receptive aphasia - takes out Wernicke's area


Superior division of dominant MCA

  • Contralateral weakness (mostly face and arm, not so much leg and foot)

  • Lower half of contralateral face is affected

  • Contralateral sensory loss

  • Contralateral hemineglect

  • Expressive aphasia (as it takes out Broca's area)


Whole non-dominant MCA

  • Contralateral weakness

  • Contralateral sensory loss

  • Contralateral hemineglect

  • Contralateral homonymous hemianopia

  • Construction apraxia (where you lose the ability to reproduce drawing or 3D shapes)

  • Spatial disorientiation


Inferior division of non-dominant MCA

  • Contralateral homonymous hemianopia or upper quadrant anopsia

  • Constructional apraxia


Superior division of non-dominant MCA

  • Contralateral weakness (mostly face and arm, not so much leg and foot)

  • Mainly the lower half of the contralateral face is affected

  • Contralateral sensory loss (including face)

  • Contralateral hemineglect


Ataxic hemiparesis

Caused by the small penetrating arteries of the MCA, or the basilar artery, affecting the posterior limb of external capsule and the pons

  • Contralateral weakness (more in the leg than the arm)

  • Contralateral ataxia

  • No facial involvement



Lateral pontine syndrome (Marie-Foix syndrome): Anterior inferior cerebellar artery

  • Ipsilateral facial weakness

  • Ipsilateral cerebellar ataxia (arm and leg)

  • Ipsilateral hearing loss, vertigo and nystagmus (CN VIII is taken out)

  • Contralateral weakness (corticospinal tract)

  • Contralateral pain and temperature loss (spinothalamic tract)


Lateral medullary syndrome (Wallenberg syndrome): Posterior inferior cerebellar artery (PICA)

  • Ipsilateral facial sensory loss

  • Ipsilateral Nystagmus

  • Ipsilateral Horners

  • Loss of gag reflex

  • Ipsilaeral ataxia with a tendency to fall to the ipsilateral side

  • Contralateral pain and temperature sensory loss in the extremities

  • Vertigo, nausea and dysphagia